I'm running a Surface Book, with a 3000x2000 resolution, DM starts to look very odd in places.

Would anything like this be realistically worth your time? It's not like I've ran into anything causing me to completely halt. Let me know and I'll start uploading a bunch more screenshots of what else is weird looking.
You are making an assumption here. What makes you think this is the issue?
It's likely not. It seems something in your windows setting is increasing the size of fonts to make them clearer, but DM isn't properly accounting for this in how it spaces everything out.